Article

White spot syndrome virus infection induces Caspase 1-mediated antiviral cell death in crustacean

2018-05-15

Abstract excerpt

In vertebrates, pyroptosis is an intensely inflammatory form of programmed cell death which is dependent on Caspase 1 activation and release of cytoplasmic cytokines including IL-1β. This death pathway is critical for controlling pathogenic infection by mobilizing immune cells and stimulating the development of adaptive immune response. In invertebrates, however, due to the lack of adaptive immune response, it is...

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Literature Corpus work: 6fdc1571-42f1-5afc-8ffc-70cf83104d29
DOI: 10.1101/322982

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