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The p62/Keap1/Nrf2 axis in the control of C-2 induced human gastric cancer cell death switching between autophagy and apoptosis

2021-01-19

Abstract excerpt

<h4>Background: </h4> Compound C-2 is a derivative of natural product Jaspine B and possesses anti-cancer activity against bladder cancer cells. However, little is known about its anti-cancer activity against gastric cancer. In this research, mechanism underlying anti-cancer effect of C-2 in gastric cancer cells was well investigated. Methods Anti-cancer activities of C-2 were determined by MTT, western blotting...

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Literature Corpus work
b88c0a02-8aae-50f3-9fdf-b127967dab4f
DOI
10.21203/rs.3.rs-147863/v1
Open publication

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The p62/Keap1/Nrf2 axis in the control of C-2 induced human gastric cancer cell death switching between autophagy and apoptosisDOI 10.21203/rs.3.rs-147863/v1
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