Peroxisome proliferator-activated receptor gamma (PPARγ) pathway mediates anticancer activity of Britannin, isolated from Inula aucheriana DC., in human gastric cancer cells

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Researchers are particularly interested in the plants of the genus <italic>Inula</italic> because of their potent medicinal applications. Britannin, a sesquiterpene lactone isolated from <italic>Inula aucheriana</italic> DC., exerts potent cytotoxicity towards various human cancers. In this study, we examined the involvement of the PPARγ pathway in the antitumor...

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• Autophagy in Disease and Therapy
• Bioactive natural compounds
• Cancer, Lipids, and Metabolism
• Cannabis and Cannabinoid Research
• Cytokine Signaling Pathways and Interactions
• Ginseng Biological Effects and Applications
• Inflammatory mediators and NSAID effects
• Peroxisome Proliferator-Activated Receptors

Identifiers and source

Literature Corpus work

93e81a1c-8ef2-5048-aca5-c14c2b506132

DOI

10.21203/rs.3.rs-2368957/v1