Article

Exosomal S100A9 Promotes Lung Metastasis of Adenoid Cystic Carcinoma via Activating Cancer-Associated Fibroblasts

2025-10-05

Abstract excerpt

<title>Abstract</title> <p>Salivary adenoid cystic carcinoma (SACC) exhibits a high incidence of lung metastasis, which primarily contributes to patient mortality. The tumor microenvironment (TME) plays a critical role in facilitating tumor progression, yet its specific contribution to ACC metastasis remains unclear. In this study, we used single-cell transcriptomic analysis of primary ACC tumors and adjacent nor...

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Literature Corpus work: b8749b9c-3ff9-5e98-9a99-9c1c7c86b514
DOI: 10.21203/rs.3.rs-7171055/v1

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