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Tumor microenvironment and immune function analysis and chemotherapy prediction of SDHB in PPGL (pheochromocytoma/ paraganglioma)

2024-02-01

Abstract excerpt

<h4>Background: </h4> SDHB mutations are risk factors for PPGL metastasis and poor prognosis. This study aimed to identify the SDHB gene signature and mechanisms in PPGL, and investigate its association with immunotherapy response. Method PPGL transcriptome, clinical, and single nucleotide mutation data were obtained from TCGA database. Univariate, LASSO, and multivariate Cox regression analysis was applied to co...

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Literature Corpus work
b86a2df4-5033-5bc0-ad25-23f7ef819328
DOI
10.21203/rs.3.rs-3909099/v1
Open publication

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Tumor microenvironment and immune function analysis and chemotherapy prediction of SDHB in PPGL (pheochromocytoma/ paraganglioma)DOI 10.21203/rs.3.rs-3909099/v1
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