Article

Characterization of genomic DNA of lactic acid bacteria for activation of plasmacytoid dendritic cells

2018-04-25

Abstract excerpt

Lactococcus lactis strain Plasma (LC-Plasma) possesses strong activity of stimulating plasmacytoid dendritic cells (pDCs) via the TLR9-Myd88 pathway. To reveal the effective genome structure for pDCs stimulatory activity, we performed an in vitro screening, using randomly selected DNA fragments from the LC-Plasma genome. The results showed that CpG motifs are necessary factor for active DNA fragment, but the copy...

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Literature Corpus work: b85ea056-0a01-5f82-89c7-a3419fa9b678
DOI: 10.1101/307074

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