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Cloning and expression of the genes involved in the production of and immunity against the bacteriocin lacticin RM.

Biochimica et biophysica acta - 29 Feb 2000

Yarmus M, Mett A, Shapira R

Abstract excerpt

The production of lacticin RM, a novel bacteriocin produced by Lactococcus lactis subsp. lactis EZ26, is associated with the presence of a 6-kb plasmid, pHU1. The information necessary for lacticin RM production and immunity was localized to a 2.5-kb SalI-Eco47III fragment. Sequencing analysis of this fragment revealed the presence of six open reading frames (ORFs). Deletion and mutation analyses showed that orfX...

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PMID: 10684973
DOI: 10.1016/s0167-4781(00)00012-9

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