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Integrative Bioinformatics Analysis Identifies Peripheral Blood Hub Genes and Establishes a Five-Gene Diagnostic Model for Long COVID

2025-06-16

Abstract excerpt

<h4>Background: </h4> Long COVID (LC) is a multisystem condition with symptoms persisting ≥3 months after SARS-CoV-2 infection. Objective biomarkers are lacking, and its immune and molecular mechanisms remain unclear. <h4>Methods: </h4>: We integrated five GEO peripheral blood transcriptome datasets (n = 1,717) and applied ComBat batch correction. Differentially expressed genes (DEGs; |log 2 FC| > 1, FDR < 0.05)...

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Literature Corpus work: b80418db-2f8b-5cdc-8599-a8b6629a801e
DOI: 10.22541/au.175010495.50732751/v1

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