Article

LINE-1 transposable element is expressed in Kaposi’s sarcoma and regulates gene expression in KSHV-infected cells

2026-05-06

Abstract excerpt

Long interspersed nuclear element-1 (LINE-1/L1) retrotransposons are expressed in various human cancers. Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi’s Sarcoma (KS) and Primary Effusion Lymphoma (PEL), which are characterized by global transcriptional reprogramming. Previously, we have found upregulation of L1 in PEL. Here, we show that knockdown of L1 in PEL cells significantly...

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Literature Corpus work: b78741e0-70b7-5b8f-ac91-5d0cbc8d18c2
DOI: 10.64898/2026.05.05.722887

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