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Stochastic modelling of a three-dimensional glycogen granule synthesis and impact of the branching enzyme

2022-11-01

Abstract excerpt

In humans, glycogen storage diseases result from metabolic inborn errors, and can lead to severe phenotypes and lethal conditions. Besides these rare diseases, glycogen is also associated to widely spread societal burdens such as diabetes. Glycogen is a branched glucose polymer synthesised and degraded by a complex set of enzymes. Over the past 50 years, the structure of glycogen has been intensively investigated....

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Literature Corpus work
b76a48d7-e03c-5d53-a1e5-d0c491ee92ba
DOI
10.1101/2022.10.31.514469
Open publication

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Stochastic modelling of a three-dimensional glycogen granule synthesis and impact of the branching enzymeDOI 10.1101/2022.10.31.514469
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