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Identification of biomarkers associated with endoplasmic reticulum stress-related cell death in osteoporosis based on bulk and single-cell transcriptomic analyses and experimental validation

2026-01-12

Abstract excerpt

<title>Abstract</title> <p> Background Osteoporosis (OP) is a metabolic bone disease characterized by low bone mineral density (BMD), and its pathogenesis involves endoplasmic reticulum (ER) stress-related cell death. This study aimed to identify diagnostic biomarkers associated with ER stress-related cell death in OP and explore their underlying mechanisms. Materials and Methods The training dataset (GSE56815...

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Literature Corpus work
b7617b21-7b1d-5e69-8c72-8f81410ba27a
DOI
10.21203/rs.3.rs-8454279/v1
Open publication

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Identification of biomarkers associated with endoplasmic reticulum stress-related cell death in osteoporosis based on bulk and single-cell transcriptomic analyses and experimental validationDOI 10.21203/rs.3.rs-8454279/v1
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