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Identification of endoplasmic reticulum stress and mitochondrial dysfunction related biomarkers in osteoporosis

14 Feb 2025

Abstract excerpt

BACKGROUND: Endoplasmic reticulum stress (ERS) and mitochondrial dysfunction (MD) involved in bone metabolism disorders. However, the particular mechanisms of ERS and MD related genes (ERS&MDRGs) in osteoporosis (OP) have not been elucidated. In present study, biomarkers related to ERS and MD in OP were identified. METHODS: Differentially expressed genes (DEGs) were obtained based on GEO dataset. ERS&MDRGs were...

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PMID: 39953608
DOI: 10.1186/s41065-025-00387-7

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