Article

MiR-221-5p Is Involved in the Regulation of Inflammatory Responses in Acute Gouty Arthritis by Targeting IL-1β

2020-07-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Gout is caused by the accumulation of deposited sodium urate (MSU) crystals in the joints. Recent studies have shown that interleukin-1β (IL-1β) is a key inflammatory mediator of acute gouty arthritis(AGA), and its level is regulated by microRNAs (miRNAs). However, the molecular mechanism of its regulation is still unclear.<bold>Methods: </bold>100 patients with...

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Literature Corpus work: b6bbd969-974e-5e76-8fb9-37407d5ae38e
DOI: 10.21203/rs.3.rs-48921/v1

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