Article

RAGE protein: COPD biomarker and case study for variant pathogenicity prediction

2025-08-04

Abstract excerpt

The structural biology of a protein is key to understanding its mechanism and plays a significant role in predicting the effects of clinical variants. New advances in pathogenicity predictors have improved their quality but interpreting the results in light of a protein’s structure and functional can still be challenging. We use the Receptor for Advanced Glycosylation End-products (RAGE), which is involved in trig...

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Literature Corpus work: b6b9c967-4b34-5a1b-bb20-d24908344cb5
DOI: 10.1101/2025.08.04.668362

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