Article

CPSF3 modulates the balance of circular and linear transcripts in hepatocellular carcinoma

2023-01-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>CircRNAs play an important role in tumorigenesis and metastasis, and their expression is comprehensively downregulated in hepatocellular carcinoma (HCC). Previous studies have shown that the polyadenylation signal<sup>1</sup> is critical for circRNA expression, while the 3’-end processing complex participates in circRNA cyclization. As a core executor of 3’-end...

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Literature Corpus work: b68b7fb5-d490-5eff-b3ad-98134e97ea82
DOI: 10.21203/rs.3.rs-2418311/v1

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