Optimising Prescription of Treatment In older patients with Mild hypertension at Increased risk of Serious adverse Events (OPTIMISE2): Protocol for a primary care based, open-label, randomised controlled non-inferiority trial

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Antihypertensive treatment is effective at reducing the risk of cardiovascular disease, but is associated with adverse events, particularly in older patients with frailty. As a result, deprescribing antihypertensive medications is recommended in some clinical guidelines despite limited evidence from a few small randomised controlled trials. The aim of the OPTI...

Topics

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• Aged
• Atherosclerosis
• Glucagon-Like Peptide-1 Receptor
• Phenotype
• Randomized Controlled Trials as Topic
• Risk Assessment
• Risk Factors
• Treatment Outcome

Identifiers and source

Literature Corpus work

b653b3c4-921a-5e40-a8d6-682bad89745f

DOI

10.21203/rs.3.rs-7048243/v1