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Anatomical distribution of Cancer Stem Cells between Enhancing Nodule and FLAIR hyperintensity in supratentorial Glioblastoma: time to recalibrate the surgical target?

2022-06-03

Abstract excerpt

It is generally accepted that Glioblastoma (GBM) arise from cancer stem cells (CSC), however, there is little evidence on their anatomical distribution. We investigated the expression and distribution of SOX-2-positive and CD133-positive CSCs both in the enhancing nodule (EN) of GBM and in the FLAIR hyperintensity zones on a surgical, histopathological series of 33 GBMs.The inclusion criterion was the intraoperati...

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Literature Corpus work
b63252d8-fca5-59f6-bc57-792d88834f11
DOI
10.21203/rs.3.rs-1708447/v1
Open publication

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Anatomical distribution of Cancer Stem Cells between Enhancing Nodule and FLAIR hyperintensity in supratentorial Glioblastoma: time to recalibrate the surgical target?DOI 10.21203/rs.3.rs-1708447/v1
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