Article
Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype.
Neuro-oncology - 1 Oct 2007
Lim Daniel A, Cha Soonmee, Mayo Mary C, Chen Mei-Hsiu, Keles Evren, VandenBerg Scott, Berger Mitchel S
Abstract excerpt
Neural stem cells with astrocyte-like characteristics exist in the human brain subventricular zone (SVZ), and these cells may give rise to glioblastoma multiforme (GBM). We therefore analyzed MRI features of GBMs in specific relation to the SVZ. We reviewed the preoperative and serial postoperative MR images of 53 patients with newly diagnosed GBM. The spatial relationship of the contrast-enhancing lesion (CEL)...
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