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Identification of a ubiquitin related gene signature for predicting prognosis and immune infiltration in breast cancer based on single cell and bulk RNA sequencing analysis

2026-03-27

Abstract excerpt

<title>Abstract</title> <p>Background Ubiquitination drives breast cancer (BC) progression, yet the clinical value of ubiquitin-related genes (UbRGs) remains underexplored. This study aimed to develop a UbRG-based prognostic model and investigate its associations with the tumor immune microenvironment (TIME) and therapeutic responses. Methods Transcriptomic and clinical data from the TCGA-BRCA cohort were analy...

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Literature Corpus work
b5e4424b-0de1-5519-8c69-50cd156e42e0
DOI
10.21203/rs.3.rs-8886340/v1
Open publication

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