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Immune-related biomarkers predict the prognosis and immune response of breast cancer based on bioinformatic analysis and machine learning.

Functional & integrative genomics - 8 Jun 2023

Zheng Xuewei, Ma Haodi, Dong Yirui, Fang Mengmiao, Wang Junxiang, Xiong Xin, Liang Jing, Han Meng, You Aimin, Yin Qinan, Huang Wenbin

Abstract excerpt

Breast cancer (BC) is the malignancy with the highest mortality rate among women, identification of immune-related biomarkers facilitates precise diagnosis and improvement of the survival rate in early-stage BC patients. 38 hub genes significantly positively correlated with tumor grade were identified based on weighted gene coexpression network analysis (WGCNA) by integrating the clinical traits and transcriptome...

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PMID: 37291471
DOI: 10.1007/s10142-023-01124-x

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