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Cross-species discovery of large structural variants reveals distinct evolutionary dynamics in primates

2026-08-28

Abstract excerpt

Large-scale structural variants (SVs) are major drivers of genome evolution and disease susceptibility, shaping lineage-specific gene content, genome architecture, and phenotypic diversity. Yet, their systematic detection across divergent species has been hindered by complex rearrangements and reference bias, limiting our understanding of their evolutionary impact. Here we present LGvar, a divergence-aware tool fo...

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Literature Corpus work: b5de7d7f-5517-5a4e-8cba-518b471c1d92
DOI: 10.64898/2026.08.28.747789

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