Article
Detection and interpretation of genomic structural variation in mammals.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Hall Ira M, Quinlan Aaron R
Abstract excerpt
Structural variation (SV) encompasses diverse types of genomic variants including deletions, duplications, inversions, transpositions, translocations, and complex rearrangements, and is now recognized to be an abundant class of genetic variation in mammals. Different individuals, or strains, of a given species can differ by thousands of variants. However, despite a large number of studies over the past decade and...
Topics
- Animals
- DNA
- DNA Copy Number Variations
- DNA Transposable Elements
- Dogs
- Gene Expression
- Genome
- Genomics
- Humans
- Mammals
- Mice
- Polymorphism, Single Nucleotide