Article

Identifying and replicating plasma proteins associated with hypertrophic cardiomyopathy severity in carriers of pathogenic <i>MYBPC3</i> variants

2026-03-30

Abstract excerpt

<h4>Background</h4> Hypertrophic cardiomyopathy (HCM) is a clinically variable disease in terms of onset and progression. Pathogenic MYBPC3 variants account for a substantial proportion of HCM diagnoses. This study sought to identify protein biomarkers associated with HCM severity. <h4>Methods</h4> Olink-assayed plasma proteins of 144 MYBPC3 pathogenic variant carriers were tested for associations with HCM se...

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Literature Corpus work: b512e745-8a1d-53d9-91a9-867670f00c32
DOI: 10.64898/2026.03.28.26349616

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