Article

Effects of reference databases’ refinements on the validity of molecular definitions of 15,371 candidate human-specific regulatory sequences

2015-09-09

Abstract excerpt

Thousands of candidate human-specific regulatory sequences (HSRS) have been identified, supporting the idea that unique to human phenotypes result from human-specific changes to genomic regulatory networks (GRNs). The sequence quality of reference genome databases is essential for the accurate definition of regulatory DNA segments as candidate HSRS. It is unclear how database improvements would affect the validity...

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Literature Corpus work: b3c080cb-70f6-5ea7-86e1-0ebf8590a520
DOI: 10.1101/026435

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