Article

A Novel Mutation in the Kringle IV Domain of LPA Gene Leading to Familial Cardiovascular Diseases

2020-02-18

Abstract excerpt

<title>Abstract</title> <p>Background This study aims to investigate the clinical characterization and causative genetic defect of a four-generation Chinese Han family with cardiovascular diseases. Methods The combined use of next-generation sequencing and qPCR technique was performed to investigate genetic pathology of familial cardiovascular diseases. Results The clinical manifestations of the family members in...

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Literature Corpus work: b30bee53-ffbb-586c-b935-f02e35c1c756
DOI: 10.21203/rs.2.19206/v2

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