Article

Lactobacilli Probiotics Prevent Amyloid-Beta Fibril Formation In Vitro

2025-04-23

Abstract excerpt

<title>Abstract</title> <p>Alzheimer's disease (AD) is characterized by the buildup of extracellular aggregated amyloid-β (Aβ) peptides, following sequential enzymatic cleavage of amyloid precursor protein (APP), along with intraneuronal accumulation of hyperphosphorylated Tau proteins (pTau) and subsequent neuronal loss. Despite extensive research, the precise mechanisms underlying Aβ, and Tau-mediated neurodege...

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Literature Corpus work: b294d8dc-5aa9-54a1-9b0a-ecb0305a7322
DOI: 10.21203/rs.3.rs-6505627/v1

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