Article

Hyperoside induces cell cycle arrest and suppresses tumorigenesis in bladder cancer through the interaction of EGFR-Ras and Fas signaling pathways

2023-08-31

Abstract excerpt

<h4>Background: </h4> Hyperoside is a natural flavonol glycoside widely found in plants and has been reported to have a variety of pharmacological effects, including anticancer abilities. However, the antitumor effect of hyperoside on bladder cancer has not been studied, and its exact mechanism and targets remain unclear. Methods The human bladder cancer cells T24 and 5637 were treated by hyperoside and evaluated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b284c10b-4b19-5bb6-87ce-23c0610f1883
DOI: 10.21203/rs.3.rs-3291461/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hyperoside induces cell cycle arrest and suppresses tumorigenesis in bladder cancer through the interaction of EGFR-Ras and Fas signaling pathwaysDOI 10.21203/rs.3.rs-3291461/v1Read

CB-5083 and luteolin synergistically induce apoptosis of bladder cancer cells via multiple mechanismsSemantic proximity Read

Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cellsSemantic proximity Read

Effects and mechanisms of AMIGO2 in proliferation, migration and drug resistance of bladder cancerSemantic proximity Read

Identification of Chemotherapeutic Dihydromyricetin With Enhanced Anti-tumor Activity and Biosafety for Muscle Invasive Bladder CancerSemantic proximity Read

Putting the Brakes on Tumorigenesis with Natural Products of Plant Origin: Insights into the Molecular Mechanisms of Actions and Immune Targets for Bladder Cancer TreatmentSemantic proximity Read

Unveiling the Potential of Watermelon Rind Extract: Impact on Cell Proliferation, Apoptosis, Senescence, and Transcriptomic Profile in Human Renal Adenocarcinoma CellsSemantic proximity Read

Transcriptome and Proteome Analysis Reveals Corosolic Acid Inhibiting Bladder Cancer via Targeting Cell Cycle and Inducing Mitophagy in Vitro and in VivoSemantic proximity Read

Cinnamomi Ramulus Inhibits the Growth of Colon Cancer Cells Via Akt/ERK Signaling PathwaysSemantic proximity Read

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner.Semantic proximity Read

Targeting Cancer Hallmarks with Epigallocatechin Gallate (EGCG): Mechanistic Basis and Therapeutic TargetsSemantic proximity Read

Hypericin-mediated regulation of miR21 and miR34a and their target genes in MCF7 breast cancer cellsSemantic proximity Read

Anti-proliferative mechanism of Huaier extract in human thyroid carcinoma cellsSemantic proximity Read