Article

A new vaccine strategy based on VLSs for use against SARS-CoV-2 variants: Evaluation of their immune effectiveness and investigation of the mechanism

2023-08-02

Abstract excerpt

<title>Abstract</title> <p>A new lipid system broadening the capacity of antigen carriage, including mRNA and protein, is established, and an assembled virus-like-structure (VLS) encapsulated mRNA of S1 protein from XBB.1 and loaded S1 protein from omicron BA.1 on the surface is identified. This characterized VLS enables to specifically augment mRNA expression in human respiratory epithelial cells and macrophages...

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Literature Corpus work: b2524212-2cdc-562a-9eb3-104f3615ec11
DOI: 10.21203/rs.3.rs-3134015/v1

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