Article

Eulerian–Lagrangian and thin film modeling of drug delivery under physiologically varying breathing in a realistic lung model

2025-07-05

Abstract excerpt

This work presents a computational approach to investigate antiviral aerosol deposition in anatomically realistic human airways under various physiological inhalation conditions. Antiviral drugs are represented as fine liquid droplets that form a thin coating on airway surfaces, primarily targeting early infection sites. The suggested method combines an Eulerian-Lagrangian discrete phase model (DPM) to track dropl...

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Identifiers and source

Literature Corpus work: b249b7dc-ca34-5a69-89e6-c26a6bc458fb
DOI: 10.1101/2025.07.01.662688

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