Article

A zebrafish leprosy model identifies interferon and plasminogen signaling as survival determinants in mycobacterial infection

2026-08-01

Abstract excerpt

<h4>ABSTRACT</h4> Although many genes are associated with leprosy, a skin and nerve infection by Mycobacterium leprae , the function of most of these genes in infection remains unknown. This is partly due to a paucity of animal models that are genetically malleable and recapitulate features of the human disease. Zebrafish, a recent leprosy model, have human-like responses to M. leprae , including macrophage-med...

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Literature Corpus work: b1aa164d-df6e-5f94-873f-a7d685af5a3d
DOI: 10.64898/2026.07.31.739979

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