Article

ODDB: Ocular Disease Database for integrated analysis of ocular disease–gene–drug relationships

2025-10-29

Abstract excerpt

Ocular diseases such as age-related macular degeneration, glaucoma, diabetic retinopathy, and inherited retinal dystrophies are leading causes of vision loss worldwide, yet existing databases often address only limited aspects of these disorders. To fill this gap, we developed the Ocular Disease Database (ODDB), a web-based resource that integrates genes, biomarkers, variants, and drugs associated to ocular diseas...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b190b289-a9b0-57eb-ab0f-b8a2e087a01b
DOI: 10.1101/2025.10.28.685137

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ODDB: Ocular Disease Database for integrated analysis of ocular disease–gene–drug relationshipsDOI 10.1101/2025.10.28.685137Read

EyeDiseases: an integrated resource for dedicating to genetic variants, gene expression and epigenetic factors of human eye diseasesSemantic proximity Read

OphthatomeTM: An integrated knowledgebase of ophthalmic diseases for translating vision research into the clinicSemantic proximity Read

Pinpointing Novel Plasma and Brain Proteins for Common Ocular Diseases: A Comprehensive Cross-Omics Integration Analysis.Semantic proximity Read

Disease-Phenotype Deconvolution in Genetic Eye Diseases Using Online Mendelian Inheritance in Man.Semantic proximity Read

'RetinoGenetics': a comprehensive mutation database for genes related to inherited retinal degeneration.Semantic proximity Read

Genome-wide association meta-analysis of 88,250 individuals highlights pleiotropic mechanisms of five ocular diseases in UK Biobank.Semantic proximity Read

The Undiagnosed Diseases Network (UDN) Solves Ocular Syndromic Diagnostic Dilemmas.Semantic proximity Read

Gene and phenome-based analysis of the shared genetic architecture of eye diseases.Semantic proximity Read

Genes and genetics in eye diseases: a genomic medicine approach for investigating hereditary and inflammatory ocular disordersSemantic proximity Read

Current gene discovery strategies for ocular conditions.Semantic proximity Read

Omics Biomarkers in OphthalmologySemantic proximity Read

A case–control collapsing analysis identifies retinal dystrophy genes associated with ophthalmic disease in patients with no pathogenic ABCA4 variantsSemantic proximity Read