Article

Less efficacy of valproic acid monotherapy may be caused by neural excitatory rebound in focal seizures

2021-11-02

Abstract excerpt

Valproic acid (VPA) represents one of the most efficient antiepileptic drugs (AEDs) with either general or focal seizures, but a certain percentage of patients are not recovered or even worse, the mechanism under this phenomenon remains unclear. Here, we retrospectively reviewed 16 patients who received awake craniotomy surgery. Intro-operative high density electrocorticogram (ECoG) was used to record the local fi...

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Literature Corpus work: b18e36c9-4237-5a3e-9e16-ff7eb4127789
DOI: 10.1101/2021.11.02.21265719

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