Article

CCN5 Activation by free or encapsulated-EGCG is required to Render Triple-negative breast cancer cell Viability and Tumor Progression

2022-03-30

Abstract excerpt

<h4>Background: </h4> and Purpose: Epigallocatechin-3-gallate (EGCG) has been considered an anticancer agent despite conflicting and discrepant bioavailability views. EGCG impairs the viability and self-renewal capacity of triple-negative breast cancer (TNBC) cells and makes them sensitive to estrogen via activating ER-α. Surprisingly, the mechanism of EGCG’s action on TNBC cells remains unclear. CCN5/WISP-2 is a...

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Literature Corpus work: b17704a5-f180-5a1a-908f-9deb9bb8930d
DOI: 10.22541/au.164864795.55156696/v1

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