Article
Integration and Gene Co-Expression Network Analysis of scRNA-seq Transcriptomes Reveal Heterogeneity and Key Functional Genes in Human Spermatogenesis
2021-06-15
Abstract excerpt
Spermatogenesis is a complex process of cellular division and differentiation that begins with spermatogonia stem cells and leads to functional spermatozoa production. However, many of the molecular mechanisms underlying this process remain unclear. Single-cell RNA sequencing (scRNA-seq) is used to sequence the entire transcriptome at the single-cell level to assess cell-to-cell variability. Here, more than 33,000...
Topics
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- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genomics and Chromatin Dynamics
- Molecular Biology Techniques and Applications
- Prenatal Screening and Diagnostics
- Renal and related cancers
- Reproductive Biology and Fertility
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- b173637e-1580-519e-8a9e-c853852fd096
- DOI
- 10.21203/rs.3.rs-611284/v1
