Article

Development of an in Vitro Model to Investigate the Regulation of ACE2 Expression and its Correlation with ACE2-Mediated Viral Entry

2022-09-20

Abstract excerpt

Because of rapid emergence and circulation of the SARS-CoV-2 variants, especially Omicron which shows increased transmissibility and resistant to antibodies, there is an urgent need to develop novel therapeutic drugs to treat COVID-19. In this study we developed an in vitro cellular model to explore the regulation of ACE2 expression and its correlation with ACE2-mediated viral entry. We examined ACE2 expression...

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Literature Corpus work: b124bca7-b35f-513b-86f9-8ee1f8ee4ff0
DOI: 10.2139/ssrn.4204687

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