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Article

Evaluation of podocyte Rac-1 induced kidney disease by modulation of TRPC5

2021-05-25

Abstract excerpt

<h4>Background</h4> Transient receptor potential channel 5 (TRPC5) is a non-selective cationic ion channel expressed in brain, kidney and other organs where its activation underlies podocyte injury in chronic kidney diseases. Specifically, it has been suggested that a podocyte TRPC5 plasma membrane relocation and channel activation following injury results from activation of Rac-1, propagating podocyte dysfunctio...

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Literature Corpus work
b10ebdae-fc51-51ac-b058-574bac759dae
DOI
10.1101/2021.05.25.445694
Open publication

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Evaluation of podocyte Rac-1 induced kidney disease by modulation of TRPC5DOI 10.1101/2021.05.25.445694
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