Article

Potential of Melittin to induce apoptosis and overcome multidrug resistance in human colon cancer cell line

2024-02-15

Abstract excerpt

In this study, the anticancer effect of Melittin was demonstrated through its antiproliferative and proapoptotic effects on HT-29 cells, as well as its ability to reverse multidrug resistance. Melittin directly affects the death receptor-dependent apoptotic pathway via increase of the Fas receptor protein expression, Caspase 8 gene expression and activity of Caspase 8. Results of decreased Caspase 9 gene and prote...

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Literature Corpus work: b0ef6380-e643-5965-9bc1-79afd3b2a71e
DOI: 10.1080/15569543.2024.2317294

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