Article

HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data

2022-10-21

Abstract excerpt

Though open chromatin may promote active transcription, gene expression responses may not be directly coordinated with changes in chromatin accessibility. Most existing methods for single-cell multi-omics data focus only on learning stationary and shared information among these modalities, overlooking modality-specific information delineating cellular states and dynamics resulting from causal relations among modal...

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Identifiers and source

Literature Corpus work: b0b33377-b832-55dc-8a8b-70094761c361
DOI: 10.1101/2022.10.17.512602

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