Article

TMAO miscompartmentalization is a reversible driver of autism pathophysiology

2024-06-03

Abstract excerpt

Autism spectrum disorder (ASD) is a complex and heterogeneous neurodevelopmental disorder. Contrary to what has been reported for genetics and gut dysbiosis, ASD appears to be very homogeneous when considering tryptophan metabolism. Indeed, multiple biochemical anomalies have been observed in most individuals with ASD. Following up on these findings, we found that ASD is strongly associated with the miscompartment...

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Literature Corpus work: b07aa15d-7e48-5e6e-af13-e62713927a75
DOI: 10.1101/2024.05.30.596635

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