Article

Elevated Microbially-Derived Metabolites in Autism: A Possible Diagnostic Screening Test for a Distinct ASD Phenotype

2025-10-02

Abstract excerpt

<title>Abstract</title> <p>Many studies have confirmed that a subset of children with autism spectrum disorder (ASD) have unusually high urinary concentrations of harmful microbially-derived metabolites (MDMs) such as p-cresol sulfate and indoxyl sulfate. We hypothesized that these MDMs may affect neurodevelopment through the gut-brain axis and that a sub-phenotype characterized by gut dysbiosis may be present in...

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Literature Corpus work: 254f2db3-9823-5342-9959-b18f116882cc
DOI: 10.21203/rs.3.rs-7643826/v1

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