Article

Selection and surveillance of 5S ribosomal RNA genes in human populations

2026-08-31

Abstract excerpt

The 5S ribosomal RNA gene is present in the human genome not once but in ~80 copies, arranged head to tail in a single array of ribosomal DNA on chromosome 1 -one of the most repetitive and least explored regions of the genome. Its product is one of the four RNAs in every ribosome and, when ribosome assembly fails, it activates the tumour suppressor p53. Whether these copies vary in sequence between people, and wh...

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Literature Corpus work: b07328dc-ed83-5b37-9857-36e531a43d8a
DOI: 10.64898/2026.08.27.26361558

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