Article

Peptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development

2021-09-15

Abstract excerpt

Fungal infection is an important health problem in Latin America, and in Brazil in particular. Paracoccidioides (P. brasiliensis and P. lutzii) is responsible for paracoccidioidomycosis, a disease that affects mainly the lungs. The glycoprotein gp43 is involved in fungi adhesion to epithelial cells, which makes this protein an interesting target of study. A specific stretch of 15 amino acids that spans the region...

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Literature Corpus work: b02b29d4-a245-53c9-9bd2-d6658045c644
DOI: 10.21203/rs.3.rs-893807/v1

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