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Article

Polymorphism in the Gene Coding for the Immunodominant Antigen gp43 from the Pathogenic Fungus <i>Paracoccidioides brasiliensis</i>

1 Nov 2000

Abstract excerpt

The gp43 glycoprotein is an immune-dominant antigen in patients with paracoccidioidomycosis (PCM). It is protective against murine PCM and is a putative virulence factor. The gp43 gene of Paracoccidioides brasiliensis B-339 is located in a 1,329-bp DNA fragment that includes two exons, a 78-bp intron, and a leader peptide-coding region of 105 bp. Polymorphism in gp43 has been suggested by the occurrence, in the...

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Identifiers

PMID: 11060052
DOI: 10.1128/jcm.38.11.3960-3966.2000

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