Article

A SARS-CoV-2 variant of concern triggers Fc effector function with increased cross-reactivity

2021-11-05

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2 variants of concern (VOCs) exhibit escape from neutralizing antibodies, causing concern about vaccine effectiveness. However, while non-neutralizing cytotoxic functions of antibodies are associated with decreased disease severity and vaccine protection, Fc effector function escape from VOCs is poorly defined. Furthermore, whether VOCs trigger Fc functions with altered specificity, as h...

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Literature Corpus work: b00bcaf3-0b4b-5c19-9203-08e440068161
DOI: 10.1101/2021.11.05.21265853

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