Article

Autoantibody profiling of cerebrospinal fluid from affective disorders and schizophrenia patients by phage display : method optimization and evaluation of selected autoantigens as candidate biomarkers

2009-01-01

Abstract excerpt

Immunoproteomics approach applied on affective disorder and schizophrenia patient CSF samples yielded a number of candidate autoantigens. An overall analysis of those candidates revealed that impairment of myelination might have a role in etiology of such psychiatric disorders. Validations were based on phage ELISA that is applied on the most prominent autoantigen candidate obtained from phage display selection. I...

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Literature Corpus work: afa3099c-b109-5831-8820-37b789e0b49f
DOI: 10.21954/ou.ro.0000f26d

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