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Identification of Alzheimer’s Disease Autoantibodies and Their Target Biomarkers by Phage Microarrays

28 May 2019

Abstract excerpt

The characterization of the humoral response in Alzheimer's disease (AD) patients might aid in detecting the disease at early stages. We have combined phage display and protein microarrays to identify AD autoantibodies and their target biomarkers. After enrichment of the T7 phage display libraries from AD and healthy brain tissue mRNA in AD-specific phages, 1536 monoclonal phages were printed on microarrays to...

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PMID: 31136180
DOI: 10.1021/acs.jproteome.9b00258

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