Article
Psychosis: an autoimmune disease?
Immunology - 1 Nov 2017
Al-Diwani Adam A J, Pollak Thomas A, Irani Sarosh R, Lennox Belinda R
Abstract excerpt
Psychotic disorders are common and disabling. Overlaps in clinical course in addition to epidemiological and genetic associations raise the possibility that autoimmune mechanisms may underlie some psychoses, potentially offering novel therapeutic approaches. Several immune loci including the major histocompatibility complex and B-cell markers CD19 and CD20 achieve genome-wide significance in schizophrenia....
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