Article

Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains

2020-11-11

Abstract excerpt

The glutaric acidurias are a group of inborn errors of metabolism with different etiologies. Glutaric aciduria type 3 (GA3) is a biochemical phenotype with uncertain clinical relevance caused by a deficiency of succinyl-CoA:glutarate-CoA transferase (SUGCT). SUGCT catalyzes the succinyl-CoA-dependent conversion of glutaric acid into glutaryl-CoA preventing urinary loss of the organic acid. Here, we describe the pr...

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Literature Corpus work: af99389a-5fd5-5b5c-8f95-ddc02d95b0a6
DOI: 10.1101/2020.11.11.378463

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