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Transplantation of high fat fed mouse microbiota into zebrafish larvae identifies MyD88-dependent acceleration of hyperlipidaemia by Gram positive cell wall components

2021-04-29

Abstract excerpt

Gut dysbiosis is an important modifier of pathologies including cardiovascular disease but our understanding of the role of individual microbes is limited. Here, we have used transplantation of mouse microbiota into microbiota-deficient zebrafish larvae to study the interaction between members of a mammalian high fat diet-associated gut microbiota with a lipid rich diet challenge in a tractable model species. We f...

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Identifiers and source

Literature Corpus work
af57130d-c33c-522b-9b5f-635fa49ca2e3
DOI
10.1101/2021.04.28.441900
Open publication

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Transplantation of high fat fed mouse microbiota into zebrafish larvae identifies MyD88-dependent acceleration of hyperlipidaemia by Gram positive cell wall componentsDOI 10.1101/2021.04.28.441900
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