Article

Increasing Autophagy ameliorate all-trans-retinal-activated NLRP3 Inflammasome 2 in human THP-1 macrophage cells

2021-08-12

Abstract excerpt

<h4>Background: </h4> Profound inflammation that mediated by innate immune sensors can be observed in retina, and is considered to play an important role in the pathogenesis of all-trans-retinal (atRAL)-caused retinal degeneration. However, the underlying mechanism remains elusive. MethodsCell viability was detected with Cell Counting Kit-8 (CCK-8). The concentration of IL-1β was evaluated using IL-1β ELISA Kits....

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Literature Corpus work: af5294c6-6473-50e8-bd5e-30ad20d36954
DOI: 10.21203/rs.3.rs-797831/v1

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